No valid Database connection found?

I’ve been working fine without any issues with targets local, Staging and Live and I am using Environmental variables to set the details of the Database.
Whilst on Local, all of a sudden, I got a message when on Target (local):

I don’t use Direct Database Connection. I have put everything in Enviro variables and its been working fine for a few weeks.

Not sure what happened all of a sudden this message has come up.

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